Profhilo before and after infographic showing treatment areas, results, and differences with fillers.

Profhilo Before and After: Real Patient Results, Timelines, and What to Expect


In the world of aesthetic medicine, patients are increasingly looking for subtle, natural-looking improvements rather than dramatic changes. Over the last decade, the focus has shifted from overfilled appearances to treatments that restore skin quality, hydration, and elasticity.

Among the most innovative injectables available today, Profhilo® has become one of the most popular choices for patients and practitioners seeking natural rejuvenation. Unlike traditional dermal fillers that add volume to specific areas, Profhilo works differently: it spreads evenly beneath the skin and stimulates collagen and elastin production through its ultrapure hyaluronic acid, providing an overall improvement in skin firmness and texture.

Because of its unique mechanism, many people are not sure what results to expect. One of the most common questions both patients and professionals face is: What results can I expect from Profhilo before and after treatment? Searching for Profhilo before and after photos online is often the first step for patients who want to visualize the changes in their skin, but understanding the science behind the treatment and the typical timeline of results is equally important.

This comprehensive guide provides an in-depth look at Profhilo before and after outcomes, explaining how the treatment works, what changes are visible at different stages, and what professionals should communicate to their patients in order to set realistic expectations.


What Is Profhilo and How Does It Work?

Profhilo is a bioremodelling injectable that contains one of the highest concentrations of hyaluronic acid (64mg/2ml). Unlike cross-linked fillers, Profhilo spreads evenly under the skin, improving:

  • Hydration
  • Elasticity
  • Firmness
  • Overall skin texture

It is injected using the BAP (Bio Aesthetic Points) technique, which ensures maximum diffusion with minimal injections.


Profhilo Before and After: Key Improvements Patients Notice

Patients often report visible changes in their skin quality rather than dramatic structural modifications.

Common Improvements:

  • Increased hydration and glow
  • Smoother fine lines and wrinkles
  • Firmer, more elastic skin
  • Healthier complexion
  • Subtle lifting effect

Profhilo Results Timeline: What to Expect Week by Week

TimelineWhat Happens
Day 1–7Small bumps at injection sites may appear but resolve within 24–48 hours. Skin feels more hydrated.
Week 2–3Initial glow and subtle firmness noticed. Collagen stimulation begins.
Week 4Second session usually performed. Boosts results and long-term effect.
Week 6–8Maximum improvement in skin texture, firmness, and hydration.
Month 6–9Results begin to gradually fade. Maintenance may be scheduled.

Before and After Profhilo: Face, Neck, and Hands

Treatment AreaBefore (Common Concerns)After (Visible Results)
FaceDullness, fine lines, loss of elasticityBrighter skin, smoother texture, firmer feel
NeckCrepiness, horizontal lines, saggingTighter appearance, hydrated, fewer wrinkles
HandsDry, thin, aged-looking skinMore plump, hydrated, youthful-looking hands

Illustration of Profhilo before and after results with improved firmness and smoother skin.
Step-by-step infographic describing the Profhilo treatment journey, including initial bumps, glow and firmness, second session, visible results, and maintenance phase.

How Long Do Profhilo Results Last?

One of the most frequent patient concerns is duration.

  • Results typically last 6–9 months, depending on metabolism, age, and lifestyle.
  • Maintenance treatments are usually recommended twice a year.

Factors That Influence Longevity:

  • Age: Younger patients metabolize hyaluronic acid faster.
  • Lifestyle: Smoking, alcohol, and sun exposure reduce longevity.
  • Skin condition: Severely dehydrated or aged skin may require more frequent sessions.

Profhilo vs Dermal Fillers: Differences in Results

AspectProfhiloTraditional Fillers
Main PurposeSkin quality, hydration, collagen stimulationVolume restoration, contouring
Before & AfterSubtle glow, smoother skinVisible volumization, reshaping
Injection TechniqueBAP (5 points per side)Multiple targeted injection points
Longevity6–9 months9–18 months depending on filler type

Profhilo Before and After Photos: What They Show

Although every patient is unique, clinical photos usually highlight:

  • Improved glow (often within the first 2–3 weeks)
  • Reduction in crepiness on the neck and décolleté
  • More youthful hands with better hydration
  • Smoother facial texture without a “done” look

Profhilo Combined With Other Treatments

Profhilo results are subtle and can be enhanced when combined with other procedures:

CombinationBenefit
Profhilo + BotoxReduces wrinkles + improves skin texture
Profhilo + FillersCombines hydration with volume restoration
Profhilo + LaserBoosts collagen + improves pigmentation
Profhilo + MicroneedlingIntensifies collagen stimulation and skin renewal

FAQs About Profhilo Before and After

1. How soon will I see results after Profhilo?
Most patients notice improvements in hydration within the first week, with optimal results after the second session.

2. Will Profhilo change my face shape?
No. Unlike fillers, Profhilo does not volumize—it enhances skin quality only.

3. Can I go back to work immediately?
Yes. It’s a lunchtime procedure with minimal downtime. Small bumps disappear in 24–48 hours.

4. Can Profhilo be used on the body?
Yes. It can be injected in areas like the neck, hands, arms, abdomen, and knees.


Clinical Insights for Professionals

For practitioners, setting patient expectations is key. Use before and after examples to:

  • Emphasize realistic outcomes (hydration, elasticity, not volume).
  • Explain the treatment timeline clearly.
  • Highlight the need for maintenance sessions.

Final Thoughts on Profhilo Before and After Results

Profhilo before and after results clearly demonstrate why this innovative injectable has become one of the most sought-after treatments in modern aesthetic medicine. Unlike volumizing fillers, Profhilo offers a unique form of skin bio-remodelling that enhances hydration, firmness, and elasticity without altering the natural contours of the face. Patients appreciate the subtle but noticeable rejuvenation, which leaves the skin looking fresher, smoother, and healthier.

For aesthetic professionals, highlighting Profhilo before and after outcomes through case studies, patient photos, and treatment timelines is essential to set realistic expectations and ensure satisfaction. Educating patients on the gradual improvements and the importance of maintenance treatments helps build trust and long-term results.

From a patient’s perspective, understanding what to expect from Profhilo before and after treatment reduces anxiety, increases confidence, and provides reassurance that the changes will look natural. Whether used on the face, neck, or hands, Profhilo offers a proven pathway to radiant, youthful-looking skin.

With the right treatment plan and proper guidance, Profhilo remains one of the most reliable ways to achieve natural-looking rejuvenation without heaviness or volume overload.

References

  1. IBSA Derma. Profhilo® – The first bio-remodelling injectable treatment with stabilized hyaluronic acid. IBSA Derma Official Website. https://www.ibsaderma.com
  2. Sparavigna, A., Tenconi, B., & De Ponti, I. (2019). Evaluation of the efficacy of a new injectable treatment based on stabilized hybrid cooperative complexes of high- and low-molecular-weight hyaluronic acid: A clinical, histological, and ultrasonographic study. Clinical, Cosmetic and Investigational Dermatology, 12, 297–305. https://doi.org/10.2147/CCID.S207564
  3. Papakonstantinou, E., & Gehring, W. (2021). Hyaluronic acid: More than a dermal filler – Bioremodelling with Profhilo®. Journal of Cosmetic Dermatology, 20(10), 3055–3062. https://doi.org/10.1111/jocd.14381

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