Juvéderm Volux is a structurally formulated hyaluronic acid filler designed specifically to define and project the jawline and chin. Due to its high density, cross-linking, and lifting capacity, it requires precise technique and a deep understanding of facial anatomy.
As jawline contouring procedures have become increasingly popular in aesthetic medicine, the importance of using the correct product with proper clinical technique has also grown. Juvéderm Volux, developed with Vycross™ technology by Allergan, offers one of the most advanced structural fillers in the professional aesthetic toolkit. However, despite its advantages, improper application can lead to clinical challenges and compromised results.
This article examines the most frequent mistakes professionals encounter when using Juvéderm Volux and presents strategies to avoid them. By understanding both the potential and the limitations of this product, healthcare providers can ensure optimal aesthetic outcomes, increased patient satisfaction, and long-term safety.
Product Characteristics
| Property | Description |
|---|---|
| Composition | Hyaluronic acid 25 mg/mL + lidocaine 0.3% |
| Technology | Vycross™ |
| Indication | Jawline and chin contouring |
| FDA Approval | August 2022 |
| Estimated Duration | Up to 18–24 months |
| Recommended Injection | Deep subcutaneous / supraperiosteal |
Source: FDA Summary of Safety and Effectiveness Data SSED – P110033/S065
Vycross™ technology combines low and high molecular weight hyaluronic acid to increase lift capacity and longevity while maintaining smooth integration into tissue. Volux is the densest and most cohesive product within the Juvéderm range, making it suitable for use in areas requiring structural support, such as the mandible and chin.
1. Injecting Volux in Incorrect or Unsupported Areas
Mistake: Administering Volux in soft tissue areas requiring less dense fillers or lacking proper bony support can lead to unnatural outcomes or nodules.
Professional Recommendation: Limit Volux application to deep structural zones, such as the mandibular angle, mandibular body, and chin. These areas benefit from the filler’s volumizing and lifting properties when injected at the supraperiosteal level. Avoid superficial areas and zones without underlying skeletal support, such as the submental region, which may not tolerate the product’s density.
Clinical Tip: Assess bone projection, skin thickness, and tissue laxity during consultation. Combine Volux with other Juvéderm fillers like Voluma or Volift in adjacent zones requiring more flexibility.
2. Overcorrecting with Excess Volume
Mistake: Overfilling is a common concern, especially in patients requesting dramatic changes. However, excess volume can cause distortion, asymmetry, and vascular complications.
Technical Solution: Adhere to conservative dosing. Begin with lower volumes and reassess at follow-up. Remember that the mandibular contour is highly responsive to small volume changes due to its proximity to the skin and its structural influence.
| Area | Suggested Initial Volume |
| Mandibular angle | 0.3–0.5 mL per side |
| Lateral jawline | 0.2–0.4 mL |
| Chin | 0.3–0.6 mL |
Overcorrection not only compromises aesthetics but also increases risk of lumpiness, product migration, and patient dissatisfaction.
3. Failing to Respect the Deep Injection Plane
Mistake: One of the most frequent technical errors is injecting Volux into superficial tissue layers, which can result in visible product, contour irregularities, or even granuloma formation.
Solution: Always aim for deep planes: supraperiosteal in the chin and angle, deep subcutaneous over the mandibular body. Use appropriate instruments such as:
- Needle: 27G, ½ inch for precise bolus in structural zones
- Cannula: 22G, 50 mm for linear or fan technique along jawline
Safety Practice: Perform aspiration before each bolus. Inject slowly and monitor resistance to reduce vascular risk.
Reference: ClinicalTrials.gov NCT03712137
4. Ignoring Anatomical and Vascular Contraindications
Mistake: Lack of anatomical knowledge is a leading cause of complications with high-density fillers. Accidental intra-arterial injection can result in necrosis or blindness.
Solution: Familiarize yourself with vascular landmarks:
- Facial artery: Crosses the mandible anterior to the masseter
- Facial vein: Parallel and posterior to the artery
- Marginal mandibular nerve: Inferior and anterior to the parotid gland
Training Tip: Use ultrasound guidance when treating high-risk zones or adopt cannula techniques to reduce vascular entry risk.
5. Inadequate Patient Preparation
Mistake: Omitting informed preparation leads to misaligned expectations and may affect aftercare compliance.
Best Practice:
- Discuss goals and limitations of Volux use
- Show example results (before/after photos)
- Document consent for off-label use if applicable
- Provide written post-treatment instructions
Patient education contributes to trust and satisfaction, especially when managing side effects like swelling, bruising, or asymmetry during the initial healing phase.
6. Lack of Proper Clinical Documentation
Mistake: Poor documentation hinders the ability to perform touch-ups, evaluate outcomes, or report adverse events to health authorities.
Solution: Standardize your documentation for each patient:
- Injection sites and volumes
- Product batch number and expiry
- Clinical photos at baseline and follow-up
- Treatment plan and follow-up notes
This becomes critical in multi-session treatments or legal cases involving complaints.
7. Using Juvéderm Volux Without Specialized Training
Mistake: Juvéderm Volux should not be used as an entry-level filler. Its high density requires experience in structural aesthetics and anatomical variation.
Solution: Attend specialized training for jawline contouring using cadaveric dissection, ultrasound anatomy, and simulation models. Training should also cover complication management, filler reversal with hyaluronidase, and patient communication techniques.
Professional Resources:
- Allergan Medical Institute programs
- IMCAS, AMWC, or FACE CME-accredited courses
- Peer-reviewed publications in journals like “Aesthetic Surgery Journal” and “Dermatologic Surgery”

Clinical Guidelines for Optimized Outcomes
| Key Area | Recommendation |
| Patient Selection | Choose individuals with well-defined goals and skeletal profile |
| Cannula vs. Needle | Cannula reduces risk; needle offers precision for deep boluses |
| Follow-up | Reassess at 2 weeks to evaluate symmetry and plan additional treatment |
| Injection Depth | Supraperiosteal in structural zones; avoid dermal or mid-subcutaneous use |
| Pain Management | Lidocaine in formulation often sufficient; optional topical anesthetic |
Trusted References
Professional Conclusion
Juvéderm Volux offers one of the most advanced options for jawline enhancement in aesthetic medicine. Its performance, durability, and ability to sculpt the lower third of the face make it a valuable asset in non-surgical facial harmonization. However, optimal outcomes rely on professional expertise, anatomical precision, and safe injection practices. Practitioners must stay updated with the latest clinical evidence, technique evolution, and product-specific guidelines to maximize success.
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