In aesthetic medicine, the Juvéderm product line is one of the most trusted and widely used families of hyaluronic acid-based dermal fillers. Developed by Allergan (AbbVie), these fillers utilize proprietary Vycross™ technology to deliver varying densities and characteristics suited to specific anatomical needs.
However, for medical professionals, choosing the appropriate Juvéderm filler can be particularly challenging due to the wide variety of formulations available, each with distinct rheological properties, indications, and injection techniques. Despite being part of the same product family, each Juvéderm filler—whether Voluma, Volux, Volift, or Volbella—has been engineered for different anatomical areas, tissue depths, and treatment goals. Misapplication or lack of understanding of these differences can lead to suboptimal aesthetic results, complications, or reduced patient satisfaction.
This is why a clear, side-by-side clinical and technical comparison is essential for practitioners aiming to deliver precise, safe, and predictable outcomes. A well-informed filler selection not only supports facial harmonization and natural results but also ensures longer-lasting effects with fewer corrections required.
This comprehensive Juvéderm filler comparison aims to assist professionals in navigating the nuances of product selection by offering a structured breakdown of the most commonly used options in the Vycross™ range. Specifically, it highlights Voluma, Volux, Volift, and Volbella, focusing on key clinical variables such as primary indications, ideal injection depth, estimated longevity, cohesivity, elasticity, and expert recommendations based on anatomical zones. The goal is to empower licensed injectors to make evidence-based decisions tailored to each patient’s facial structure and treatment plan.
Product Overview Table
| Product | Indications | Injection Depth | HA Concentration | Cohesivity | Duration |
|---|---|---|---|---|---|
| Voluma | Cheek augmentation, midface lift | Deep subcutaneous / bone | 20 mg/mL | High | Up to 24 months |
| Volux | Jawline and chin definition | Supraperiosteal / deep SC | 25 mg/mL | Very High | Up to 24 months |
| Volift | Nasolabial folds, moderate volume | Mid to deep dermis | 17.5 mg/mL | Moderate | 12–18 months |
| Volbella | Lip contour, perioral lines | Superficial dermis | 15 mg/mL | Low | 9–12 months |
SC = Subcutaneous
Juvéderm Voluma: Structural Volume for Midface
Best for: Malar augmentation, cheekbones, deep volume loss.
- Rheology: Voluma has high G’ (elasticity) for lift and projection.
- Technique Tip: Inject on bone with a bolus technique using needle (27G) or long cannula (22G). Avoid superficial layers to prevent lumpiness.
- Clinical Insight: Ideal for pan-facial rejuvenation protocols in combination with lighter fillers.
Juvéderm Volux: High-Density for Jawline Contour
Best for: Lower third harmonization, chin enhancement, mandibular angle.
- Rheology: Highest cohesivity and density in the Juvéderm range.
- Technique Tip: Supraperiosteal bolus or linear threads along jawline using 27G needle or 22G cannula. Always aspirate.
- Clinical Insight: Not suitable for superficial tissues. Highly effective in male jawline masculinization.
Juvéderm Volift: Versatile Filler for Folds and Contour
Best for: Nasolabial folds, marionette lines, light volumization.
- Rheology: Softer than Voluma; allows dynamic movement.
- Technique Tip: Inject mid to deep dermis. Blend with fanning technique for soft transitions.
- Clinical Insight: Excellent for combination treatments with Voluma in older patients.
Juvéderm Volbella: Precision in Superficial and Dynamic Zones
Best for: Lip definition, smokers lines, tear troughs (with caution).
- Rheology: Lowest G’ and viscosity; soft and spreadable.
- Technique Tip: Microdroplets in superficial dermis with 30G needle.
- Clinical Insight: Use minimal volume to avoid overcorrection in delicate areas.
Clinical Comparison Chart
| Feature | Voluma | Volux | Volift | Volbella |
| Lift Capacity | High | Very High | Moderate | Low |
| Flexibility | Low | Low | Moderate | High |
| Injection Precision | Structural | Structural | Moderate | Very High |
| Best for | Midface | Jawline/Chin | Folds | Lips/Lines |
| Volume Needed | 1–2 mL | 1–2 mL | 0.5–1 mL | 0.3–0.5 mL |
| Cannula Compatible | Yes | Yes | Yes | Yes |
Trusted References
Final Note for Professionals
Selecting the right Juvéderm product depends on your patient’s anatomy, treatment goals, and tissue quality. This comparison aims to simplify your clinical decision-making by outlining the core characteristics of each filler in the Vycross family. For optimal outcomes, always combine product knowledge with anatomical precision and validated technique.
Explore our full portfolio of Juvéderm products and clinical supplies at: https://glowhealth.eu/